Have any bad side effects been reported?
So far, the only notable side effects observed in earlier, smaller trials are mild injection site reactions, which occur in small numbers of people and tend to resolve quickly. The ORION-4 trial is designed to detect rare or long-term side effects that may not have been seen in these earlier studies. The trial is monitored regularly by an independent committee of experts who would advise the coordinating team if any important safety concerns emerged in the trial data.