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Investigators

Louise Bowman

Louise Bowman

Principal/Chief Investigator

Marion Mafham

Marion Mafham

Co-Principal Investigator

David Preiss

David Preiss

Co-Principal Investigator

Statistician

Head and shoulders photo of Bruno da Costa

Bruno da Costa

Senior Scientist


CLINICAL RESEARCH FELLOWS

The Clinical Research Fellows are the doctors working on the trial at the coordinating centre.

 
The ORION-4 team at the Joint Annual Collaborators meeting in May 2022

Photo of ORION-4 team members at the May 2022 Collaborators meeting.


CENTRAL COORDINATING OFFICE (CCO) TRIAL STAFF

The trial managers are responsible for setting up and running the study with help from the trial administrators. The call centre staff are trained to respond to calls from people invited to join the trial, study participants, their doctors and site staff.  

SENIOR TRIAL MANAGERS: Rejive Dayanandan, Liz Wincott

TRIAL MANAGER UK TEAM LEAD:  Zahra Madgwick

TRIAL MANAGERS:  Cristina Badin, Holly Bradford, Kate Gardiner (UK & USA), Natasha Grewal, John Nolan, Michelle Nunn, Kate Sawyer, Karen Taylor (USA).

TRIAL ADMINISTRATORS: Sue Hurley, Alison Timadjer, Monique Willett

CALL CENTRE STAFF: Charles Cutting, Monika Raj, Ian Roure.


CENTRAL COORDINATING OFFICE TRAINING AND MONITORING TEAM

This team trains and supports staff at ORION-4 sites, including undertaking monitoring visits to check that the study is being run correctly and provide advice and support for the site staff running the ORION-4 clinics.

CCO HEAD OF MONITORING: Meera Mistry

CLINICAL TRIAL MONITORS: Mary Green, Malvika Gursahani, Yara Neves Silva, Sajda Perveen  

TRAINING LEAD: Jenny Ingell


TRIAL MASTER FILE TEAM

The Trial Master File (TMF) team makes sure that all the essential documents for the trial are managed correctly. This is important for trials like ORION-4 as healthcare regulators need to be able to audit these documents to check that the trial was run correctly. 

TMF MANAGERS: Chrissie Ambrose, Ryan Cotter, Bridget Henderson, Violetta Howard, Hannah Kingston  


IT DEVELOPMENT TEAM

This team is responsible for developing the IT systems for the trial, including systems used in the Central Coordinating Centre laboratory. The senior analysts prepare the trial data so it is ready to be analysed by the trial statisticians.

Mike Lay (Lead), Rach AitSadi, Alex Baxter, Lukasz Danel, Sonja Grotjahn, Edward Humphreys, Rijo Kurian, Archie Maskill, Ola Murawska, Rachel Raff, James Thompson, Matt Wallis, Allen Young

LABORATORY IT DEVELOPMENT: Nick Goodwin (Lead), Mark Caple, Luminita Condurache, Jon Tyler

TESTING:  Bob Goodenough (Lead), Guanguo Cui, Charles Daniels, Angela Field, Ashley Lawson, Youcef Mostefai, Dheeptha Radhakrishnan, Samee Syed, Shuang Xia

TRIAL ANALYSIS PROGRAMMING: Karl Wallendszus (Lead),  Yonghong Bu, Rosie Cretney, ManHo Cheung, Will Stevens.

METADATA SUPPORT: Heather Halls, Kate Wilson.

CENTRAL COORDINATING OFFICE LABORATORY STAFF

LABORATORY SCIENTIFIC DIRECTOR: Mike Hill

SENIOR LABORATORY MANAGER: Stewart Moffat